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. Author manuscript; available in PMC: 2014 Jul 7.
Published in final edited form as: Cold Spring Harb Symp Quant Biol. 2011 Nov 23;76:235–246. doi: 10.1101/sqb.2011.76.010694

Figure 6.

Figure 6

HCMV hijacks host cell metabolism, directing carbon toward fatty acids. Metabolic map shows concentration and flux changes induced by HCMV infection. Font sizes represent metabolite pool sizes in uninfected cells, arrow widths show net fluxes in uninfected cells, and the color scale indicates the fold change in concentrations and fluxes induced by HCMV. Metabolites in gray were not measured. Note that the strongest flux changes are in the TCA cycle and its efflux toward fatty acids (Munger et al. 2008).