Figure 4.
GR splice variants. The GR primary transcript is composed of 9 exons. Exon 2 encodes the NTD, exons 3-4 encode the DBD, and exons 5-9 encode the hinge region (H) and LBD. GRα results from splicing exon 8 to the beginning of exon 9. GRβ, GRγ, GR-A, and GR-P are generated by the depicted alternative splicing events.