Table 2. Prevalence and Severity of Sleep Disordered Breathing (SDB) stratified by HIV status and HAART use.
| HIV – | All HIV+ | P-valuea | HIV+/HAART+ | HIV+/HAART− | P-valueb | |
| (N = 60) | (N = 99) | (N = 58) | (N = 41) | |||
| A. Prevalence | ||||||
| Prevalence By Respiratory Disturbance Index (RDI) | ||||||
| RDI ≥5 events/h | 52 (86.7) | 71 (71.7) | 0.03 | 41 (70.7)* | 30 (73.2) | 0.83 |
| RDI ≥10 events/h | 41 (68.3) | 56 (56.6) | 0.18 | 34 (58.6) | 22 (53.7) | 1.00 |
| RDI ≥15 events/h | 35 (58.3) | 46 (46.5) | 0.19 | 28 (48.3) | 18 (43.9) | 0.84 |
| Prevalence By Severity (events/h) | ||||||
| Normal (<5.0) | 8 (13.3) | 28 (28.3) | 0.03 | 17 (29.3) | 11 (30.6) | 0.13 |
| Mild (5.0–14.9) | 17 (28.3) | 25 (25.3) | 13 (22.4) | 12 (28.6) | ||
| Moderate (15.0–29.9) | 19 (31.7) | 35 (35.4) | 22 (37.9) | 13 (31.7) | ||
| Severe (≥30.0) | 16 (26.7) | 11 (11.1) | 6 (10.3) | 5 (12.2) | ||
| B. RDI and Respiratory Arousal Index Distribution | ||||||
| RDI (events/h)c | ||||||
| NREM | 18.1 (5.4–30.5) | 11.2(3.8–21.6) | 0.06 | 11.7 (3.8–21.6) | 10.2 (3.8–21.2) | 0.95 |
| REM | 19.3 (8.6–35.3) | 14.0 (5.9–31.6) | 0.18 | 13.3 (4.7–31.6) | 15.9 (7.5–28.3) | 0.67 |
| Total | 21.0 (7.9–30.9) | 11.9(4.1–24.1) | 0.02 | 12.1* (4.1–23.6) | 11.9* (4.7–24.1) | 0.97 |
| Respiratory Arousal Indexd (events/h) | ||||||
| NREM | 11.9 (3.4–23.1) | 6.2(1.9–14.6) | 0.02 | 6.8 (2.3–15.9) | 5.3* (1.8–12.1) | 0.67 |
| REM | 6.8 (3.6–15.4) | 7.0(2.4–17.2) | 0.40 | 7.0 (2.3–17.4) | 7.4 (2.6–13.6) | 0.99 |
| Total | 12.0 (4.2–21.3) | 6.1(2.7–15.3) | 0.02 | 7.4 (3.1–16.3) | 5.6* (2.5–14.2) | 0.56 |
Values shown are N(%) or median (25th percentile –75th percentile).
a
P-values are for comparison of HIV− to HIV+ participants.
b
P-values are for comparison of HIV+/HAART+ to HIV+/HAART− participants.
c
RDI is defined as the number of apneas and hypopneas (a ≥ 3% desaturation or an arousal) per hour of sleep.
d
The respiratory arousal index is the number of arousals associated with an apnea or hypopnea per hour of sleep.
*P < 0.05, compared to HIV−.
Comparisons of data represented by medians were performed using the Wilcoxon ranksum test for 2 group comparisons. Comparisons of categorical data represented by percent were performed using chi-square analysis and the Fisher’s exact test.