Figure 3.
PTK7 is over-expressed in human ADC. A. Forest plot of PTK7 expression across all discovery and validation meta-analysis datasets. The x-axis is the standardized mean difference between ADC and normal on a log2 scale. Thus, a value of 1 signifies a 2-fold difference in gene expression between cancer and normal. B. Representative images of PTK7 expression in two patient-derived xenograft (PDX) specimens. C. Representative images of PTK7 staining of normal lung and ADC spanning grades 1-3. Scale bars represent 50μm.