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. Author manuscript; available in PMC: 2015 May 15.
Published in final edited form as: Cancer Res. 2014 Mar 20;74(10):2892–2902. doi: 10.1158/0008-5472.CAN-13-2775

Figure 6.

Figure 6

PTK7 depletion in three NSCLC cell lines decreases tumor burden in a xenotransplantation assay. A. Tumor volume over time of xenografted H1299 with control shRNA against luciferase (shLUC), or 2 independent hairpins against PTK7. Error bars represent standard error of the mean (s.e.m) and significant p-values correspond to <0.01 (**) or <0.001 (***) when compared to the shLUC control. Values are mean ± SEM (n = 4-8). B. Representative ex vivo images of H1299 tumors. C and D. Same figures for H2009 cell line. E and F. Same figures for H23 cell line. G. Staining of PTK7, pHH3 and CC3 by IHC in the H1299 xenografts. H. Quantification of pHH3-positive cells per field of view (n=6) I. Quantification of CC3-positive cells per field of view (n=6).