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. Author manuscript; available in PMC: 2014 Jul 7.
Published in final edited form as: Addict Biol. 2012 Sep 17;19(1):37–48. doi: 10.1111/j.1369-1600.2012.00496.x

Figure 3.

Figure 3

Extinction of cocaine self-administration in adult mice exposed to nicotine (n = 6) or vehicle (n = 7) during adolescence. The number of previously active lever presses was significantly greater (*P < 0.05) on the first day of extinction relative to all other days, which did not differ significantly. Additionally, on all 6 days of extinction, the number of lever presses on the previously active lever was significantly greater (P < 0.05) than the number on the previously inactive lever. Performance of adolescent nicotine- and vehicle-exposed mice did not differ significantly during the extinction stage