Table 2.
Parameter values for the simulation test-case scenario.
| S | largest cell dimension | 10 μm |
| NR | number of receptors per cell | 106 |
| W | animal weight | 20 g |
| ID | injected dose of doxorubicin | 33 mg/kg |
| PID | percentage of injected dose in tumor | 1% |
| E | number of molecules of doxorubicin per particle | 104 |
| P | IC90 of doxorubicin | 10 μM |
| M | molar mass of doxorubicin | 543.52 g/mol |
| VT | tumor volume | 5 mm × 5 mm × 5 mm |
| L | desired tissue penetration depth | 200 μm |
| T | time at which PID is measured | 48 hours |
| TC | circulation time of the nanoparticles | 24 hours |