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. Author manuscript; available in PMC: 2014 Jul 7.
Published in final edited form as: Nano Today. 2013 Dec 1;8(6):566–576. doi: 10.1016/j.nantod.2013.11.001

Table 2.

Parameter values for the simulation test-case scenario.

S largest cell dimension 10 μm
NR number of receptors per cell 106
W animal weight 20 g
ID injected dose of doxorubicin 33 mg/kg
PID percentage of injected dose in tumor 1%
E number of molecules of doxorubicin per particle 104
P IC90 of doxorubicin 10 μM
M molar mass of doxorubicin 543.52 g/mol
VT tumor volume 5 mm × 5 mm × 5 mm
L desired tissue penetration depth 200 μm
T time at which PID is measured 48 hours
TC circulation time of the nanoparticles 24 hours