. 2010 Dec 8;18(1):34–40. doi: 10.1111/j.1755-5949.2010.00226.x

Table 1.

Magnetic resonance spectroscopy (1H MRS at 4 Tesla) findings in ADHD subjects and in controls

	Controls (N= 12)	ADHD (N= 10)		Controls versus ADHD untreated	ADHD untreated versus ADHD treated
	Controls (N= 12)	Untreated (Baseline)	Treated (OROS MPH at 6 weeks)	Controls versus ADHD untreated	ADHD untreated versus ADHD treated

		MRS ratios: Mean ± SD		Statistics: t statistic;	Cohen's d; P‐value
Glutamate/Ino (Glu/Ino)	1.56 ± 0.34	1.79 ± 0.42	1.50 ± 0.45	d= 0.60	d= 0.45
				t ₍₂₀₎= 1.44	t ₍₉₎= 1.43
				P= 0.17	P= 0.19
Glutamine/Ino (Gln/Ino)	1.02 ± 0.60	1.30 ± 0.61	1.08 ± 0.43	d= 0.45	d= 0.31
				t ₍₂₀₎= 1.05	t ₍₉₎= 0.97
				P= 0.31	P= 0.36
Glx/Ino^a	2.59 ± 0.87	3.09 ± 0.80	2.58 ± 0.73	d= 0.59	d= 0.54
				t ₍₂₀₎= 1.40	t ₍₉₎= 1.71
				P= 0.18	P= 0.12

^aGlx, combined Glutamate & Glutamine.