Table 1.
Comparison of published cases of imquimod-induced vitiligo or vitiligo-like depigmentation in English literature
| Case | Author (year) | Age (year)/ gender | Diagnosis | Site | Clinical presentation | Pathology | Family genetic history |
|---|---|---|---|---|---|---|---|
| 1 |
Brown et al. 2005
[5] |
25/M |
Vitiligo-like hypopigmentation |
Scrotum |
Multiple depigmented patches on the scrotum ranging from 3 mm to 2 cm |
No |
No report |
| 2 |
Stefanaki et al. 2006
[6] |
32/M |
Vitiligo |
Dorsal surface of penis, scrotum, and pubic area |
Vitiligo, slight repigmentation |
No |
Yes |
| 3 |
Senel et al. 2007
[8] |
32 M |
Vitiligo-like depigmentation |
Glans penis, shaft of penis, and scrotum |
Depigmented areas |
No |
No |
| 4 |
Al-Dujaili et al. 2007
[7] |
21/M |
Vitiligo |
Penile shaft and scrotum |
Depigmented patches |
No |
No report |
| 5 |
Serrão et al. 2008
[9] |
26/M |
Vitiligo-like depigmentation |
Shaft of penis |
Vitiligo-like depigmentation |
No |
No report |
| 6 |
Zhang et al. 2011
[10] |
25/M |
Vitiligo |
Coronoid sulcus and corpus penis |
Ivory-white patch nearly 4 × 2 cm |
No |
No report |
| 7 |
Zhang et al. 2011
[10] |
22/M |
Vitiligo |
Penis |
Depigmented patches with irregular pigmented edges |
No |
No report |
| 8 | Wang et al. 2013 [11] | 36/F | Vitiligo | Perineum and perianal | Depigmentation patches with clear demarcation lines | No | No |