Table 1.
Baseline Demographic and Pulmonary Function Data.
| Baseline n = 321 |
6 Month n = 211 |
6 Month HRCT n = 169 |
12 Month n = 144 |
12 Month HRCT n = 118 |
|
|---|---|---|---|---|---|
| Age at diagnosis, mean (SD) | 63.9 (9.7) | 63.2 (10.0) | 63.8 (9.8) | 62.3 (10.0) | 62.7 (10.0) |
| Male, n (%) | 217 (67.6) | 151 (71.6) | 127 (75.1) | 102 (70.8) | 88 (74.6) |
| Ever tobacco use, n (%) | 236 (73.5) | 162 (76.8) | 131 (77.5) | 109 (75.7) | 89 (75.4) |
| Tobacco pack-years, mean (SD) | 26.2 (27.5) | 27.2 (28.4) | 27.2 (28.0) | 26.6 (27.6) | 27.3 (28.1) |
| Surgical lung biopsy, n (%) | 245 (76.3) | 158 (74.9) | 118 (69.8) | 113 (78.5) | 88 (74.6) |
| Follow-up years, median (95%CI) | 5.2 (4.9–6.1) | 5.4 (5.1–7.0) | 5.1 (4.7–6.1) | 6.6 (5.3–7.7) | 5.4 (5.0–7.0) |
| Pulmonary Function | |||||
| FEV1 % predicted, mean (SD) | 79.2 (19.0) | 79.1 (17.2) | 79.1 (17.0) | 80.7 (18.6) | 80.9 (18.5) |
| FVC % predicted, mean (SD) | 67.6 (16.8) | 68.0 (15.8) | 67.7 (15.3) | 69.0 (16.4) | 69.0 (16.3) |
| DLCO % predicted, mean (SD) | 44.5 (16.2) | 46.2 (15.3) | 44.9 (14.8) | 48.0 (16.1) | 46.6 (15.6) |
| CPI, mean (SD) | 53.2 (12.4) | 51.8 (11.7) | 52.8 (11.2) | 50.7 (12.1) | 51.6 (11.7) |
Definition of abbreviations: n = number of patients, SD = standard deviation, CI = confidence interval, FEV1 = forced expiratory volume in 1 second, FVC = forced vital capacity, DLCO = diffusing capacity for carbon monoxide, CPI = composite physiologic index, HRCT = high resolution computed tomography.