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Microphotographs illustrating CAIX immunohistochemistry expression in malignant cells of lung cancer tissue specimens (×40). A, combined CAIX strong membrane and cytoplasmic expressions in a squamous cell carcinoma. B, strong CAIX membrane expression in a squamous cell carcinoma. C, moderate CAIX cytoplasmic expression in an adenocarcinoma. D, lack of CAIX expression in a poorly differentiated adenocarcinoma.
