Table 3.
Membrane carbonic anhydrase IX in different patient groups
| Group | N | mCAIX* (mean ± standard deviation, median) | P value |
|---|---|---|---|
|
| |||
| Histopathologic Type: | |||
| Adenocarcinoma | 133 | 60.4 ± 91.1, 0 | <0.0001 |
| Squamous cell carcinoma | 77 | 118.0 ± 104.5, 103 | |
|
| |||
| Nodal Stage: | |||
| N0 | 169 | 75.6 ± 97.1, 30 | 0.063 |
| N1 | 41 | 106.2 ± 108.4, 60 | |
|
| |||
| Pathological Stage: | |||
| I | 164 | 75.3 ± 96.6, 30 | 0.077 |
| II | 46 | 103.9 ± 109.2, 60 | |
|
| |||
| Differentiation: | |||
| Well | 47 | 63.2 ± 99.4, 0 | 0.043 |
| Moderate | 87 | 76.6 ± 96.2, 20 | |
| Poor | 75 | 97.9 ± 103.6, 60 | |
|
| |||
| EGFR: | |||
| Mutation | 12 | 27.5 ± 56.5, 0 | 0.074 |
| Wild type | 129 | 72.3 ± 95.4, 20 | |
|
| |||
| KRAS: | |||
| Mutation | 12 | 82.1 ± 107.2, 35 | 0.88 |
| Wild type | 128 | 66.5 ± 91.7, 18.33 | |
|
| |||
| Gender: | |||
| Female | 110 | 79.6 ± 102.4, 20 | 0.3879 |
| Male | 100 | 83.7 ± 97.6, 42.5 | |
|
| |||
| Race: | |||
| Caucasian | 194 | 77.3 ± 96.2, 30 | 0.090 |
| Other | 16 | 133.5 ± 130.2, 72.5 | |
|
| |||
| Smoking History: | |||
| Current | 84 | 81.0 ± 97.4, 37.5 | 0.605 |
| Former | 94 | 87.3 ± 104.3, 42.5 | |
| Never | 32 | 66.1 ± 94.4, 15 | |
*
mCAIX range for each category was 0–300