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. 2014 Jul 7;9(7):e101109. doi: 10.1371/journal.pone.0101109

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© 2014 Luz, Shamir

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The conditional mean firing rate of the presynaptic cell given that the postsynaptic cell has fired at time , is plotted as function of time. (A) Excitatory synapse (B) Inhibitory synapse. Each set of dots (color coded) is the conditional mean firing rate calculated over 1000 hours of simulation time with fixed synaptic weights and presynaptic firing rates on all inputs. The different sets correspond to a different presynaptic weight () on a single synapse on which the STA was measured. The respective dashed lines show the numerical fitting of the form where takes the revised formula: . For every type of synapse, i.e., excitatory (in A) and inhibitory (in B), the parameters describing , namely , were chosen to minimize the least square difference between the analytic expression and the numerical estimation of the STA. These parameters were then used to calculate .

Inline graphic — The conditional mean firing rate of the presynaptic cell given that the postsynaptic cell has fired at time , is plotted as function of time. (A) Excitatory synapse (B) Inhibitory synapse. Each set of dots (color coded) is the conditional mean firing rate calculated over 1000 hours of simulation time with fixed synaptic weights and presynaptic firing rates on all inputs. The different sets correspond to a different presynaptic weight () on a single synapse on which the STA was measured. The respective dashed lines show the numerical fitting of the form where takes the revised formula: . For every type of synapse, i.e., excitatory (in A) and inhibitory (in B), the parameters describing , namely , were chosen to minimize the least square difference between the analytic expression and the numerical estimation of the STA. These parameters were then used to calculate .