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. Author manuscript; available in PMC: 2014 Jul 7.
Published in final edited form as: Curr Top Med Chem. 2012;12(17):1869–1882. doi: 10.2174/156802612804547335

Table 1.

Protein families best represented in the Pocketome encyclopedia.

Family # of entries Fraction of the Pocketome (%)
Protein Kinase 113 5.72
Cytochrome P450 34 1.72
Nuclear Hormone Receptor 33 1.67
Peptidase S1 30 1.52
GST 26 1.32
Calycin 25 1.23
Class-II Aminoacyl-tRNA Synthetase 22 1.11
Short-chain Dehydrogenases/reductases 21 1.06
G-protein Coupled Receptor 1 16 0.81
AB Hydrolase 15 0.76
Peptidase C1 12 0.61
Class-I Aminoacyl-tRNA Synthetase 12 0.61
Aldo/keto Reductase 11 0.56
TPP Enzyme 11 0.56
Hepacivirus Polyprotein 10 0.51
Class-I PLP-dependent Aminotransferase 10 0.51
Dihydrofolate Reductase 10 0.51
Phospholipase A2 10 0.51