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. Author manuscript; available in PMC: 2014 Jul 7.
Published in final edited form as: Diabetologia. 2009 May 26;52(8):1589–1598. doi: 10.1007/s00125-009-1384-x

Fig. 2.

Fig. 2

SDF-1 activates WNT signalling, as indicated by TOPflash luciferase activity:FOPflash activity, in INS-1 cells. a Time course of the TOPflash:FOPflash ratio of INS-1 cells treated with 1 nmol/l SDF-1. b Ratio of TOPflash:FOPflash activity in INS-1 cells treated with increasing doses of SDF-1. c Increasing doses of AMD3100 (AMD) antagonised 1 nmol/l SDF-1 activation of WNT signalling. The x-axes for b and c are logarithmic scales. All values are relative to the value of untreated INS-1 cells. Data were normalised for transfection efficiency by co-transfected beta-galactosidase and are presented as means±SD of three experiments