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. 2014 Jun 27;9:687–695. doi: 10.2147/COPD.S47792

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© 2014 Malerba et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Least squares mean (95% CI) change from baseline for trough FEV₁ in the treatment arms.

Note: Reprinted from Lancet Respir Med, 2, Decramer M, Anzueto A, Kerwin E, et al, Efficacy and safety of umeclidinium plus vilanterol versus tiotropium, vilanterol, or umeclidinium monotherapies over 24 weeks in patients with chronic obstructive pulmonary disease: results from two multicentre, blinded, randomised controlled trials, pages 472–486.⁴³ Copyright © 2014, with permission from Elsevier.

Abbreviations: CI, confidence interval; FEV₁, forced expiratory volume in 1 second.