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. 2014 Jun 23;5:43–62. doi: 10.2147/PROM.S42735

Figure 1.

Figure 1

Efficacy of maintenance antipsychotic medication versus placebo in schizophrenia (65 trials, n=6,493).

Notes: Data are n/N (%) unless otherwise stated. The random effects model by DerSimonian and Laird144 was used throughout, with weights calculated by the Mantel–Haenszel method. *Weighted by sample size of individual trials. Because of space limitations, we did not use the display suggested by Altman.145 Reprinted from The Lancet, 379, Leucht S, Tardy M, Komossa K, et al, Antipsychotic drugs versus placebo for relapse prevention in schizophrenia: a systematic review and meta-analysis, 2063–2071, Copyright © 2012, with permission from Elsevier.11

Abbreviations: AE, adverse event; MD, movement disorder; n, number of participants with an event; N, number of studies; CI, confidence interval; NNTB/NNTH, number needed to treat to benefit/harm; H, harm; B, benefit.