Fig. (7). The effects of resveratrol on TGF-β-modulated EMT-related genes of pancreatic cancer cells.
A, Treatment with resveratrol for 48 h diminished the effects of TGF-β on the expression of E-cadherin, N-cadherin, vimentin, MMP-2, and MMP-9 at the mRNA level in BxPC-3 and Panc-1 cells, as determined by QT-PCR. (B) Treatment with resveratrol for 48 h diminished the effects of TGF-β on the expression of EMT-related genes at the protein level in BxPC-3 and Panc-1 cells, as determined by Western blotting. *P < 0.05 compared with the control group; #P < 0.05 compared with the TGF-β group.