Figure 2.

CGRP relaxation dose-response curves for spontaneously contracting myometrium from women in the nonpregnant state (circles), during pregnancy but not in labor (squares), and in labor (triangles). Relaxation responses, expressed as percent of control activity at each dose of CGRP applied, were analyzed by repeated-measures ANOVA among 3 groups. Each point represents mean ± SEM for 6 patients. Asterisks indicate a statistically significant difference vs. other 2 groups (P < 0.05 by ANOVA followed by Bonferroni t test).