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. 2014 Apr 29;2:820–831. doi: 10.1016/j.redox.2014.04.011

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© 2014 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).

PMC Copyright notice

Fig. 1 — Effect of aspartame (40 mg/kg bwt) on superoxide dismutase (SOD) activity (units/mg of tissue protein) in rat brain discrete regions. CC = cerebral cortex; CB = cerebellum, MB = midbrain; PM = ponsmedulla; HP = hippocampus; HY = hypothalamus. Comparison and analysis were done by the one-way analysis of variance (ANOVA) (n = 6), control group was compared with MTX control group and aspartame MTX group, MTX control group was compared with Aspartame MTX group. Control, MTX control – Methotrexate treated group; Asp + MTX – Aspartame + Methotrexate treated group.The data from various groups for the individual parameters are presented as bar diagram with mean ± SD. significance fixed at P < 0.05, aspartame treated group when compared to control significance is marked as * and MTX treated groups significance is marked as #.