Figure A2.

Complete remission rates by dose groups. The rates of complete remission were 15.0% under placebo compared with 31.4% in the 3.2 g LT-02 group (P=0.089); the other rates were 27.5% (0.8 g LT-02) and 22.0% (1.6 g LT-02). Complete remission was defined by a mean Simple Clinical Colitis Activity Index (SCCAI) of <3 without blood in stool. When adding a normal stool frequency to this definition, the remission rate then increased by factor 2.3, from 12.5% in the placebo group to 28.6% in the highest LT-02 dose group (P=0.105). The blue columns show the rates for partial remission defined by an SCCAI <5.