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. 2014 Mar 17;11(3):253–262. doi: 10.1038/cmi.2013.67

Figure 4.

Figure 4

Th17 cells promote growth of first-trimester human trophoblasts by secreting IL-17. (a) Effect of Th17 cells-derived supernatants on the proliferation of trophoblasts with or without neutralizing antibody to IL-17. (b) The effect of different concentrations of rhIL-17A on the proliferation of trophoblasts. (c) Comparison of trophoblast proliferation induced by rhIL-17A or Th17 cell-derived supernatants. (d) Effect of rhIL-17 on the apoptosis of trophoblasts. (e) Effect of Th17 cell-derived supernatants on trophoblast apotopsis. Flow cytometry plot is a representative of three experiments. *P<0.05; **P<0.01; error bars: s.e.m. s.e.m., standard error of the mean; Th17, T helper 17; Th17 sup, Th17 cell-derived supernatant.