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Glomerular cell death and apoptosis detected by (a) TUNEL staining and (b) staining for nuclei containing single-stranded DNA (ssDNA) at 48 hours after induction of anti–Thy 1.1 nephritis in rats receiving the VEGF165 aptamer (n = 6) or PEG alone (n = 6). TUNEL-stained and ssDNA-positive cells were separated into those that localized to endothelial cell layers and others.
