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Mesangial changes on days 2 and 6 after induction of anti–Thy 1.1 nephritis in rats receiving the VEGF165 aptamer (n = 6) or PEG alone (n = 6). Shown is a semiquantitative evaluation of the glomerular de novo expression of α-smooth muscle actin, PDGF B-chain, type IV collagen, and fibronectin.
