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Shown are the receptor (RPTPe) and non-receptor (cyt-PTPe) forms of PTP Epsilon, SHP1, SHP2, PTP1B, the 48kDa and 45 kDa forms of TC-PTP, and PTEN. Vertical rectangles represent PTP domains in all the PTPs. Also shown are the SH2, C2, PDZ, and H (hydrophobic ER-targeting motif) domains of the various PTPs. Asterisks mark critical C-terminal tyrosines (PTPe) or nuclear localization signals (TC-PTP).
