Skip to main content
. 1999 Oct 1;104(7):937–945. doi: 10.1172/JCI7637

Figure 6.

Figure 6

Effect of dose escalation of inhaled NO on nitrosylated hemoglobin, expressed as the percentage moles of NO per moles of heme subunits. For 3 hours before NO inhalation, the mean percentage of nitrosylated hemoglobin in the arterial blood was 0.004% and in the venous blood, 0.004%. There is a significant stepwise increase in nitrosylated hemoglobin during NO inhalation in both arterial (0.011% on 40 ppm, 0.016% on 60 ppm, and 0.022% on 80 ppm) and venous (0.014% on 40 ppm, 0.016% on 60 ppm, and 0.016% on 80 ppm) blood (P < 0.05 for all increases except the venous sample at 40 ppm, for which P = 0.075). A significant arterial-venous difference was observed on 80 ppm inhaled NO (P = 0.02).