Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Jul 7;206(1):29–43. doi: 10.1083/jcb.201312078

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2014 Ensminger et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

PMC Copyright notice

Figure 6. — DSBs formed after MMS at BER intermediates cause translocations. Chromatid-type translocations in (A) CHO-9 (WT) and EM-C11 (XRCC1-deficient) cells, (B) WT and MPG^−/− MEFs, (C) siRNA-treated A549 cells, and (D) PARPi-treated WT and MPG^−/− MEFs. Data in panels A–C were obtained from the experiments performed for Fig. 4, B–D. Data in D were obtained from the experiments performed for Fig. 5 D (±SEM from 3–5 experiments). *, P < 0.05; **, P < 0.01; ***, P < 0.001.