Table 2.
List of general model parameters
| Symbol | Model parameter | Value | Reference |
| Parameters used in both models | |||
| Lkin | Kinetochore linear size | 430 nm | Estimated based on McDonald et al., 1992 |
| katt | Rate of binding events between new MTs and the kinetochore | 4 min−1 | Materials and methods part 2 section “Choice of model parameters” |
| Ntotal | Total number of NDC80 complexes per kinetochore | Nsites × N0 = 600 | By definition |
| Δt | Time step in computational algorithm | 1 ms | Materials and methods |
| Additional parameters in the model with repetitive sites | |||
| Nsites | Number of MT binding sites per kinetochore | 50 | Estimated based on McEwen et al., 1997 |
| N0 | Number of NDC80 complexes per MT binding site | 12 | Johnston et al., 2010; Lawrimore et al., 2011; Aravamudhan et al., 2013 |
| Additional parameters in the lawn model | |||
| LNDC80 | Length of NDC80 complex | 60 nm | Ciferri et al., 2008 |
| Lmin | Minimal distance between KMTs | 35 nm | McDonald et al., 1992 |
These values are based on published data for PtK1 cells (for details see Materials and methods). All calculations in this work were carried out using these parameter values unless stated otherwise.