Table 3.
Restrictive versus liberal red blood cell (RBC) transfusion strategy in cardiac patients: randomized clinical trials
| |
Health problem |
Patients |
Mortality
b
|
|
|---|---|---|---|---|
| First author, year a | (n) | (95% CI) | P -value | |
| Adults |
|
|
|
|
| Bracey, 1999 [73] |
CABG |
428 |
RR: 0.52 (0.13 to 2.04) |
NS |
| Carson, 2011 [74] |
Hip surgeryc |
2,016 |
ARR: 0.9 (−1.5 to +3.4) |
NS |
| Cooper, 2001 [52] |
Myocardial infarction |
46 |
8% versus 5% |
1.0 |
| Hajjar, 2012 [23] |
Cardiac surgery |
502 |
6% versus 5% |
0.93 |
| Hébert, 2001 [75] |
ICU cardiac patients |
357 |
22.5% versus 22.7% |
1.00 |
| Johnson, 1992 [76] |
CABG |
38 |
No differenced |
NS |
| Shehata, 2012 [19] |
Cardiac surgery |
50 |
16% versus 4% |
NS |
| Pediatric cardiac surgery |
|
|
|
|
| Cholette, 2011 [77] |
Cyanotic |
60 |
1 death |
NS |
| de Gast-Bakker, 2013 [78] |
Non-cyanotic |
107 |
No death |
NS |
| Willems, 2010 [79] | Non-cyanotic | 125 | 12.7% versus 6.5% | 0.36 |
ARR: absolute risk reduction; CABG: coronary artery bypass graft; CI: confidence interval; RBC: red blood cell; NS: not statistically significant.
aYear of publication.
bRestrictive versus liberal transfusion strategy.
cHip surgery in patients older than 50 years with atherosclerosis.
dNo significant difference in duration or degree of exercise was demonstrated between the two groups.