Skip to main content
. Author manuscript; available in PMC: 2014 Jul 8.
Published in final edited form as: Cancer Res. 2012 Dec 26;73(5):1502–1513. doi: 10.1158/0008-5472.CAN-12-2560

Table 2.

Immunogenic proteins identified in neu-transgenic mouse cancer cell lysate. Case-to-control ratios are an average of two analyzed blood draws.

Gene Description Subcellular Localization Case-to-Control Ratios Q-value (FDR)
Time Point #1 Time Point #2
Aldoa Fructose-bisphosphate aldolase A Cytoplasm 1.25 0.7687 0.0297
Aldoc Fructose-bisphosphate aldolase C Cytoplasm 1.25 0.7687 0.0297
Arpc2 Actin-related protein 2/3 complex subunit 2 Cytoplasm 2.69 0.7687 0.0463
Dnajb14 DnaJ homolog subfamily B member 14 Nucleus 1.96 0.7687 0.0297
Eno1 Alpha-enolase Cytoplasm 1.38 0.7687 0.0238
Hist1h1b Histone H1.5 Nucleus 2.69 0.7687 0.0463
Hist1h1d Histone H1.3 Nucleus 2.01 0.3306 0.0118
Hist1h2ba Histone H2B type 1-A Nucleus 1.45 0.7398 0.0126
Hist1h2bc Histone H2B Nucleus 2.01 0.3306 0.0118
Hnrnpa2b1 Heterogeneous nuclear ribonucleoproteins A2/B1 Nucleus 1.20 0.7687 0.0463
Krt18 Keratin, type I cytoskeletal 18 Cytoplasm 2.51 0.7687 0.0297
Krt7 Keratin, type II cytoskeletal 7 Cytoplasm 2.51 0.7948 0.0297
Krt8 Keratin, type II cytoskeletal 8 Cytoplasm 2.51 0.7948 0.0186
Mdh2 Malate dehydrogenase, mitochondrial Cytoplasm 1.69 0.7398 0.0126
Nme1 Nucleoside diphosphate kinase A Nucleus 1.38 0.7687 0.0238
Nme2 Nucleoside diphosphate kinase B Nucleus 1.20 0.7687 0.0463
Nsfl1c NSFL1 cofactor p47 Cytoplasm 2.39 0.7398 0.0397
Pdia3 Protein disulfide-isomerase A3 Cytoplasm 2.37 0.7687 0.0278
Pkm2 Pyruvate kinase isozymes M1/M2 Cytoplasm 1.72 0.7687 0.0323
Rbm3 Putative RNA-binding protein 3 Nucleus 1.34 0.7687 0.0297
Serbp1 Plasminogen activator inhibitor 1 RNA-binding protein Nucleus 2.22 0.3306 0.0118
Sfrs3 Serine/arginine-rich splicing factor 3 Nucleus 4.77 0.3306 0.0118
Sfrs7 Serine/arginine-rich splicing factor 7 Nucleus 2.01 0.7687 0.0444
Ubfd1 Ubiquitin domain-containing protein UBFD1 Unknown 2.02 0.7687 0.0434
Znf518b Zinc finger protein 518B Unknown 2.69 0.7687 0.0463

q-values based on all 2,808 arrayed fractions

q-values based on 120 fractions significantly elevated (p<0.05) in cases in time point #1