FIG. 7.
Effect of apocynin on chronic cerebral hypoperfusion-induced Morris water maze (MWM) performance deficits in rats. Spatial memory evaluation using time latency (A), search error (B), swimming speed (C) % time in target quadrant (D), and (E) time latency in visible platform test. n=6/group, *p<0.05, ***p<0.001 versus Sham control, #p<0.05, ###p<0.001 versus 2VO control. Sham control, sham-operated rats treated with vehicle; SC+Apo, sham-operated rats treated with apocynin (10 mg/kg/day for 8 weeks); 2VO control, 2VO-operated rats treated with vehicle; 2VO+Apo, 2VO-operated rats treated with apocynin; NS, not significant.