Table 1.

Synthesis of trimethylbenz[e]indolium deriviatives (Biotage Initiator 2.0).

Entry	R	Time (min)	Temp (°C)	Avg. Yield (%)	Lit. time (h)	Lit. yield (%)	MP (°C)
1	CH3	25	120	92	0.25	86 [23]	220–225
2	CH2CH3	30	135	65	24	73 [24]	225–230
3	(CH2)2CH3	10	140	75	N/A	N/A	142–145
4	(CH2)3CH3	15	140	69	20	57 [25]	120–124
5	(CH2)4CH3	10	145	65	1.5	24 [9]	137–139
6	(CH2)2OH	15	120	64	N/A	N/A	160–164
7	(CH2)5CO2H	30	145	82	48	37 [9]	174–177
8	(CH2)4SO3	30	145	51	2.5	70 [8]	80–85