Figure 2.

Input interface for COGNAC where: (A) users can initially select between three types of search options; the example presented shows the option to upload a user provider query being selected. (B) A follow-up interface proceeding the initial options prompts users to select the type of interaction to search for based on the representative tree graphs for the interaction of interest; the example presented shows the selection of a sextuple arrangement. (C) An additional search specification option where users can define the bases for the query involved in the sextuple arrangement that has been selected in (B); users have the option of having the query design facilitated by a mini JSmol window depicting the molecular structure for each base.