Skip to main content
. Author manuscript; available in PMC: 2014 Jul 8.
Published in final edited form as: Theor Popul Biol. 2011 Dec 9;82(4):275–282. doi: 10.1016/j.tpb.2011.12.001

Figure 6.

Figure 6

For birth-rate profiles ranging from that reported for Costa Rica (steep decline starting around 1985; solid line) to constant birth through the period (horizontal dashed line), we estimated the sensitivity of the cumulative number infected to vaccination coverage achieved in infants (y axis) for coverage levels of 0 (black line), 0.1 (red line), 0.3 (green line), 0.4 (blue line) and 0.5 (turquoise line); and likewise for the sensitivity for the number of CRS cases. For both, sensitivity is consistently <0 indicating that an increase in vaccination always reduces cumulative cases and cumulative CRS cases over this time-horizon; however, greater effect is observed for lower coverage levels, and for the CRS burden, the direction of effects may shift with coverage levels, see text.