Table 1.
Patient Demographics of Study Population
| Variable | All patients, n = 88 |
Unresectable at referral, n = 7 |
Metastasis before resection, n = 15 |
Successfully resected, n = 66 |
p Value |
|---|---|---|---|---|---|
|
| |||||
| Sex, n (%) | |||||
| Female | 43 (49) | 2 (29) | 10 (67) | 31 (47) | NS |
| Male | 45(51) | 5 (71) | 5 (33) | 35 (53) | |
|
| |||||
| Race, n (%) | |||||
| Caucasian | 74 (85) | 7 (100) | 12 (80) | 55 (83) | |
| African-American | 2 (2) | 0 (0) | 1 (7) | 1 (15) | NS |
| Hispanic | 9 (10) | 0 (0) | 2 (13) | 7 (11) | |
| Asian | 2 (2) | 0 (0) | 0 (0) | 2 (3) | |
| Other | 1 (1) | 0 (0) | 0 (0) | 1 (1.5) | |
|
| |||||
| Age at referral, y | NS | ||||
| Mean | 58.1 | 54.9 | 56.3 | 58.8 | |
| SD | 11.6 | 17.2 | 9.7 | 11.4 | |
|
| |||||
| Time interval from first resection attempt to referral/re-staging, d |
|||||
| Mean | 44.3 | 31.1 | 58.4 | 42.5 | NS |
| SD | 28.7 | 14.1 | 26.9 | 29.3 | |
|
| |||||
| Previous center, n (%) | |||||
| Academic | 50 (57) | 3 (43) | 6 (40) | 41 (62) | |
| Community | 25 (28) | 4 (57) | 4 (27) | 17 (26) | NS |
| International | 13 (15) | 0 (0) | 5 (33) | 8 (12) | |
|
| |||||
| Previous biliary/GI bypass, n (%) |
NS | ||||
| No | 23 (26) | 3 (43) | 4 (27) | 16 (24) | |
| Yes | 65 (73) | 4 (57) | 11 (73) | 50 (76) | |
|
| |||||
| Neoadjuvant therapy before second resection attempt, n (%) |
NS | ||||
| No | 2 (13) | 5 ( 8) | |||
| Yes | 13 (87) | 61 (92) | |||
|
| |||||
| Initial CA19-9 | |||||
| Mean | 299 | 824 | 120.5 | 303.2 | NS |
| SD | 773.8 | 617 | 97 | 817 | |
|
| |||||
| Preop CA19-9 | |||||
| Mean | 106.6 | - | 96.3 | 113.2 | NS |
| SD | 191.8 | 82.3 | 211 | ||
|
| |||||
| Fold-change in CA19-9 | |||||
| Mean | 0.69 | - | 0.97 | 0.68 | NS |
| SD | 0.63 | 0.74 | 0.65 | ||
|
| |||||
| Time interval from first to second resection attempt, mo |
|||||
| Mean | 5.6 | 5.8 | NS | ||
| SD | 2.7 | 4.1 | |||