Figure 3. Stereotypic behaviors of female rats over the 30 min following administration of saline (CTR) or cocaine to acute (ACT) or repeated cocaine exposure (RPT) rats on the challenge treatment day, according to the different hormonal conditions. A, Sham-operated (SHAM) female rats. B, Ovariectomized female rats. C, Ovariectomized female rats treated with progesterone plus estradiol. D, Ovariectomized female rats treated with progesterone. E, Ovariectomized female rats treated with estradiol. Data are reported as means±SE. *P<0.05 compared to CTR; ^XP<0.05 compared to ACT (two-way repeated measures ANOVA followed by the Student-Newman-Keuls test).