Table 2.

 Healthcare utilisation. Comparison of number of hospital admissions per patient and hospital days per patient in 12 months after admission. Values are means (standard deviations) unless stated otherwise

Variables	Usual care	Early rehabilitation	Adjusted for site only*		Adjusted for covariates†
			Incidence rate ratio (95% CI)	P value	Incidence rate ratio (95% CI)	P value
No of hospital admissions
Intention to treat:
Total	.1.60 (2.29)	1.48 (1.89)	1.02 (0.76 to 1.35)	0.9	0.98 (0.74 to 1.30)	0.9
Respiratory	1.20 (1.94)	1.10 (1.64)	1.02 (0.73 to 1.41)	0.9	0.99 (0.72 to 1.37)	1.0
Non-respiratory	0.39 (0.90)	0.39 (0.81)	1.04 (0.66 to 1.64)	0.9	1.09 (0.71 to 1.70)	0.7
Per protocol:
Total	1.67 (2.39)	1.49 (1.87)	0.92 (0.68 to 1.26)	0.6	0.91 (0.67 to 1.22)	0.5
Respiratory	1.28 (2.02)	1.14 (1.65)	0.95 (0.67 to 1.34)	0.8	0.94 (0.67 to 1.33)	0.7
Non-respiratory	0.39 (0.92)	0.35 (0.75)	0.87 (0.52 to 1.45)	0.6	0.95 (0.58 to 1.56)	0.9
No of hospital days
Intention to treat:
Total	14.8 (27.7)	12.0 (18.0)	0.95 (0.63 to 1.44)	0.8	0.88 (0.58 to 1.34)	0.6
Respiratory	11.2 (23.1)	9.1 (18.5)	0.97 (0.60 to 1.59)	0.9	0.93 (0.56 to 1.53)	0.8
Non-respiratory	3.6 (12.0)	3.5 (9.3)	1.24 (0.57 to 2.68)	0.6	1.17 (0.55 to 2.46)	0.7
Per protocol:
Total	15.4 (28.7)	11.1 (16.2)	0.81 (0.52 to 1.28)	0.4	0.75 (0.48 to 1.19)	0.2
Respiratory	11.9 (24.0)	8.2 (13.7)	0.83 (0.49 to 1.41)	0.5	0.80 (0.47 to 1.38)	0.4
Non-respiratory	3.5 (12.0)	2.9 (8.0)	0.95 (0.39 to 2.28)	0.9	1.16 (0.50 to 2.73)	0.7

Table shows both intention to treat and per protocol analyses, defined as participants who remained within the study during the six week intervention period. Analyses are shown both unadjusted and adjusted for covariates. Incident rate ratio is relative to the usual care group and offset for time exposed (time to death).

*Adjusted for site only.

†Adjusted for site, age, diagnosis, previous hospital admissions, quadriceps strength at baseline, Medical Research Council dyspnoea grade, and number of comorbidities.