FIG. 5.

Transplanted ovarian-cell-like cells formed blood vessels and follicle-like structures in vivo. (A) In the fat around the kidney, increased blood vessel formation was observed around transplanted cells and scaffold (arrows). (B) Transplanted cells and scaffold (arrow) was observed under the kidney capsule (arrowhead: kidney cortex). (C) Occasionally, blood vessels were found within the transplants (star). (D) In the subcutaneous fat in the dorsal neck area, PKH26-positive transplanted cells were observed, and some of them formed round ring-like structure (black arrow) around blood vessel (white arrow). (E) In the cell-transplanted fat tissue around the kidney, a round follicle-like structure (arrow) was sometimes observed with PKH26-positive cells. (F) In the fat tissue, PKH26-positive cells are usually detected as round ring-like structures (arrows). Scale bar=100 μm. Color images available online at www.liebertpub.com/scd