Figure 5. Effect of diet, genotype, and haplotype on respiratory complex activities.
Mitochondrial respiratory complexes activities were measured for (A) complex I, (B) complex II–III, (C) complex IV, (D) complex V, and (E) citrate synthase (CS) activity in liver mitochondria of WT and MNX mice fed control and atherogenic diets. Results are expressed as mean nmol/sec/mg protein ± SE, n=3–4 (Complex I), n=4–6 (Complex II–III), n=4–12 (Complex IV), n=4–6 (Complex V), and n=4–12 (CS). *p<0.05 or **p<0.0001, compared to corresponding control diet counterpart. ANOVA results are provided in Supplemental Table 1 and p values for pair-wise comparisons are provided in Supplemental Table 3.
