Table 1.
Uterine microRNAs (mirn) significantly regulated by estrogen based upon microRNA microarray analysis.
| Estrogen effect | Relative level of expression1 |
|---|---|
| Up-regulated | |
| mmu-mirn451 | Intermediate (9,999 – 2,000 units) |
| mmu-mirn429 | Intermediate (9,999 – 2,000 units) |
| mmu-mirn99b | Intermediate (9,999 – 2,000 units) |
| mmu-mirn155 | Low (1,999 – 500 units) |
| mmu-mirn7a | Low (1,999 – 500 units) |
| Down-regulated | |
| mmu-mirn24 | High (100,000 – 10,000 units) |
| mmu-mirn181b | Intermediate (9,999 – 2,000 units) |
| Biphasic | |
| mmu-mirn150 | Intermediate (9,999 – 2,000 units) |
| mmu-mirn720 | Low (1,999 – 500 units) |
| mmu-mirn204 | Low (1,999 – 500 units) |
1
Levels of expression were arbitrarily assigned based upon Cy3/Cy5 intensity images as described in “Materials and Methods” using the scale: High (100,000 to 10,000 units), Intermediate (9,999 – 2,000 units), and Low (1,999 – 500 units). We considered signal intensities below 500 units an insignificant level of expression.