The passive avoidance test STL1 (short memory) and STL2 (long memory) results of intact, STZ (750 μg/rat in 10 μL ACSF at d 1 and 3), castration, castrated of STZ icv injection, sham operated of Cast+STZ and vehicle of STZ-lesion rats. Each bar represent the mean±SEM of STL time (s). n=8 rat for each group. cP<0.01 when compared with intact, sham operated and vehicle of STZ group (STZ=stroptozotocin, Cas=castration, V=vehicle).