Effects of pravastatin, paroxetine and their comedication on the levels of fasting serum glucose (A), insulin (B), total cholesterol (C) and triglyceride (D) in rats during the treatments. Symbols represent CON (black-bar), HFD (white bar), DM (diagonally-striped-bar), DM-PR (cross-hatched-bar), DM-PA (zigzag-striped-bars) and DM-CO (horizontally-striped-bar). Data represent the mean±SEM of 4–6 rats. bP<0.05, cP<0.01 vs DM rats. eP<0.05, fP<0.01 vs DM-PR rats. hP<0.05, iP<0.01 vs DM-PA rats.