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. 2014 May 5;35(6):825–831. doi: 10.1038/aps.2013.195

Figure 1.

Figure 1

DAPT strengthens t-AUCB-induced cell growth suppression. U251 and U87 cells were treated for 48 h with DMSO (vehicle control), 2 μmol/L DAPT only, 200 μmol/L t-AUCB, or 200 μmol/L t-AUCB with a 4-h pre-treatment of 2 μmol/L DAPT. Cell growth was detected using cell counting kit-8 (CCK-8) and measured by the OD values. The results showed that t-AUCB can induce cell growth inhibition, but the pre-treatment of DAPT significantly strengthened the cell growth inhibitory effect induced by t-AUCB. DAPT causes no cell growth inhibition. aP>0.05, bP<0.05 vs vehicle. fP<0.01 vs t-AUCB.