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Characterization of mammary branching morphogenesis in the presence of 1,2,4-bis-aryloxadiazole analogs. (a) Representative images and (b) dose-response analysis for branching in primary MECs. Scale bar = 40 μm. Calculated EC50 values: compound 1 (1.2 +/− 0.4 μM), compound 2 (1.4 +/− 0.1 μM), compound 8 (2.2 +/− 0.1 μM), compound 9 (3.2 +/− 0.1 μM), compound 10 (>10 μM).
