Figure 2.
Effects of Gal-3 silencing on tumor cell biological characteristics. There was no differences in cell proliferation between control and experimental groups in any of the cell lines (A. Gal-3 siRNA vs controls, PSCC-4=0.509; PCAL27=0.366). However, scratch assay demonstrated that cell migration was dramatically decreased in experimental groups after Gal-3-siRNA transfection (B). Cell invasion was decreased in cells treated with Gal-3-siRNA, when compared with the control groups (C. Gal-3 siRNA vs controls, cPSCC-4<0.01; cPCAL27<0.01).