Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Transfection with Gal-3-siRNA affects β-catenin expression. Inhibition of Gal-3 gene expression affected the protein expression of β-catenin in SCC-4 and CAL27 cells (A. Gal-3 siRNA vs controls, cPSCC-4<0.01; cPCAL27<0.01), while its mRNA expression was unaffected in both cell lines (B. Gal-3 siRNA vs controls, PSCC-4=0.830; PCAL27=0.940). The immunostaining of β-catenin in cytoplasm and nucleus was decreased in Gal-3 silenced cells compared with control group (C).
