Skip to main content
. Author manuscript; available in PMC: 2014 Jul 8.
Published in final edited form as: J Neurochem. 2014 Apr 19;130(1):4–28. doi: 10.1111/jnc.12715

Fig. 4.

Fig. 4

Beta-site amyloid cleaving enzyme (BACE)2 regulates pigmentation in mice and melanophore migration in zebrafish. (a) Deletion of Bace2 in mice leads to dilution of coat color (Rochin et al. 2013). Note the black coat normally seen in the C57Bl/6 strain as observed in control and Bace1 knockout mice. (b) Deletion of Bace2 in zebrafish alters the shape and migration of melanophores (van Bebber et al. 2013). Whole fish (left panels); boxed areas are enlarged to show details near end of yolk sac extension (middle panels) and fin (right panels).