Table 2.
Characteristics of patients with clinical benefit
| Pts with clinical benefit on bicalutamide |
AR% | ER% | PgR% | HER2 | Site of testing |
Site of metastases |
Prior therapy LABC/MBC |
DOR on prior therapy, wks |
DOR on bicalutamide, wks |
|---|---|---|---|---|---|---|---|---|---|
| #1 | 10–20 | 1 | 0 | Neg | P | LN | 0 | NA | 231+ |
| #2 | >80 | 3 | 0 | Neg | Met | GI | 0 | NA | 54 |
| #3 | >80 | 0 | 0 | −/+ | P | Breast LN | 1 | NR | 25 |
| #4 | >90 | 0 | 0 | Neg | P | LN Bone | 1 | 158 | 35 |
| #5 | >50 | 0 | 0 | Neg | P | LN Bone | 1 | 15 | 43+ |
Abbreviations: DOR, duration of response; GI, gastrointestinal; LABC, locally advanced breast cancer; LN, lymph node; Met, metastasis; NA, not applicable; NR, no response; P, primary tumor.