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Bicalutamide-related adverse events per NCI CTCAE version 3
| Toxicity | Grade 1 (n) |
Grade 2 (n) |
Grade 3 (n) |
|---|---|---|---|
| AST | 5 | 1 | 1 |
| ALT | 5 | 1 | |
| Hyperbilirubinemia | 1 | ||
| Alkaline phosphatase | 1 | 1 | |
| Nausea | 1 | ||
| Pain | |||
| Headache, back, other | 3 | ||
| Breast | 3 | ||
| Limb | 3 | ||
| Constipation | 1 | ||
| Anorexia | 3 | 1 | |
| Fatigue | 5 | 1 | |
| Hemoglobin | 1 | ||
| Vaginal dryness | 1 | ||
| Diarrhea | 3 | ||
| Hot flashes | 6 | ||
| Limb edema | 6 |
NOTE: Grade 1 toxicities reported in >10% of patients (n = 28). No grade 4 or 5 events or treatment-related serious adverse events observed.
