Table 1.
Pt. No. |
Age (y), Gender |
Eye | Clinical presentation |
VA | Treatment modality |
Radiation dose (dose @ isodose × fractions) |
Optic nerve isodose (range) |
Retinal isodose (range) |
Visual outcome |
Radiologic outcome |
Toxicity | Follow-up (mo) |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 46, F | Right | VA loss | Finger counting at 3 ft. | FCRT | 6 Gy @ 80% × 6 = 36 Gy | 40–95% | 10–20% | 4/200, improved visual field and VA | Tumor regression | Eyelid edema | 151 |
2 | 47, F | Left | Visual field loss, diminished color vision | 20/20 | FCRT | 1.8 Gy × 30 = 54 Gy (isodose NA) | NA | NA | Improved visual field | Stable | None | 132 |
3 | 39, M | Left | Visual field loss | 20/20 | FCRT | 1.8 Gy @ 90% × 30 = 54 Gy | 90% (1.90–2.01 Gy) | 50% | Improved visual field | Stable | Radiation-induced retinopathy | 121 |
4 | 44, F | Right | Right blindness, orbital pain, headache, proptosis | — | FCRT | 1.8 Gy @ 90% × 30 = 54 Gy | 95–100% (1.90–2.0 Gy) | NA | Stable visual examination findings | Stable | None | 107 |
5 | 59, F | Left | Visual field and VA loss | 20/300 | FCRT | 1.8 Gy @ 98% × 30 = 54 Gy | 98% (1.81–1.84 Gy) | 98% (0.04–1.81 Gy) | 20/40, improved visual field and VA | Stable | None | 90 |
6 | 45, M | Left | Visual loss | 20/200 | FCRT | 1.8 Gy × 30 = 54 Gy (isodose NA) | NA | NA | Improved | Stable | None | 78 |
7 | 45, M | Left | Visual field loss | 20/20 | FCRT | 1.8 Gy @ 90% × 30 = 54 Gy | 90% | 98% | Improved visual field | Stable | None | 80 |
8 | 44, F | Left | Visual loss | 20/40 | FCRT | 1.8 Gy @ 98% × 28 = 50.4 Gy | 98% (1.83–1.85 Gy) | 72–98% (1.34–1.82 Gy) | Stable | Stable | None | 62 |
9 | 46, F | Right | Visual field and VA loss | 20/30 | FCRT | 1.8 Gy @ 90% × 28 = 50.4 Gy | 90% (1.58–2.10 Gy) | 40% (0.08–1.36 Gy) | 20/25, improved visual field and VA | Tumor regression | None | 61 |
Abbreviations: Pt. No. = patient number; VA = visual acuity; FCRT = functional conformal radiotherapy; NA = not available.